this post was submitted on 12 Jul 2024
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[–] witty_username@feddit.nl 21 points 11 months ago (3 children)

I'm convinced that the Alzheimer's field is one of the areas of research that will be looked back upon with disillusionment.
Tau tangles and beta plaques have been fiercely and dogmatically pursued as causes and therapeutic targets of Alzheimer's disease. However, it is becoming increasingly clear that these aggregations are likely a consequence of the disease that does not necessarily present an avenue for therapy. I.e. the harmful part of the disease probably acts upstream of or in parallel to the accumulation of the tau and beta aggregations

[–] Snowflake@sh.itjust.works 25 points 11 months ago (1 children)

All because Sylvain Lesné and team published a fraudulent research paper in 2006. The field has possibly lost a decade of time and money.

[–] amenji@programming.dev 8 points 11 months ago

TIL. Damn.

Reminds me of the how early the covid policies were based on age-old misconceptions about aerosols.

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