Did you try running a scan for malware? I usually use ClamAV. It's a simple, FOSS anti-virus scanner for Linux. Can run it from the terminal or install a version with a GUI if you'd prefer that.
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Yes, did a ClamAV with recursive scan, no hits.
Edit: typo
Last time I heard about weird audio playing it was Steam's built-in soundtrack player picking up all kinds of weird stuff and randomly playing it (or getting triggered through some shortcut or something)... just to rule it out, do you have Steam installed?
I do. But I counter with this: I had never even heard of the band Karma Factory until that soundbyte played. With the help of an F-droid app on my phone, "Audile", I was able to quickly mic the soundbyte and that helped me figure out the song clip. There is absolutely no chance Steam factored into this lolfest.