Brotato

Glutton's gameplay revolves around eating Consumables and gaining Explosion Damage from it. You only gain the explosion damage if you're at full health. So try to stay at full HP by either avoid taking damage, or by having some Healing. Since you consume a lot of consumables, you might benefit from increasing your consumable healing with the items [Lemonade] or [Weird Food]

You can get more consumables to drop by increasing your Luck Stat, buying the [Tree] or [Garden] item. Using the [Pruner] can also be quite powerful.

Pickup Range does not affect consumables while you are at full HP; you always have to walk directly onto the fruit to activate the explosion when you're unhurt.

Spicy Sauce

Glutton has some weird interactions with Spicy Sauces. If you have 1 or more Spicy Sauces, the damage is simply added on to the Glutton's innate explosion ability instead of triggering on its own. This makes Spicy Sauce a quite powerful pickup on Glutton, since the sauces will trigger 100% of the time, using the bigger explosion size of Glutton's ability.

Crit

Glutton's Explosion can crit for 1.5 times damage and the base crit chance is 3%. This isn't listed in the tooltips.