I'm really sorry to read this, I can't imagine how heartbreaking it is,
We were in a very similar situation, 2 small slightly older girls (5) and 1 rambunctious little boy (who quickly became a very big boy), we probably messed up thinking we would need to protect the kitten from the girls, ended up exactly the opposite. (Our final solution, and reason for writing this anecdote) We bought squirt guns and guarded the favorite victim like she was the president, it's taken months, but he's finally starting to get it through his skull that we don't need to play 24 hours a day. My wife has the patience of a saint, and fortunately has gotten to work from home a lot.
I hope you find peace, we can't rescue all of them.