No, not really. Programming requires understanding of the underlying hardware, at least to a certain extent. Otherwise performance issues will look like dark magic and optimizing anything would be impossible.
Where do you start debugging if something goes wrong with the software and your information level is this low/ do you look at network stats? CPU utilization, paging/swapping? Is the hard disk bandwidth the bottleneck? Without at least some passable understanding of a computer architecture people like this just throw up their hands, or throw whatever tricks they know at the wall and see what sticks.
Cant watch Ashford episodes without thinking about this connection.