yes, i believe the intention here (as is outlined in the paper you linked) is to target viruses before they infect a cell for the greatest chance of preventing what you described? but again, its really unclear to me without the original paper but that link in the article isn't working which really sucks.
windowlicker
joined 2 years ago
i'm a molecular biologist and would love to see the actual paper (because i think this article is horribly written and really doesn't explain this very well), but there exists research already for this concept. hypothetically, it would be extremely difficult for a virus to mutate to block siRNAs as they target entire essential genes, such as structural ones or essential replication proteins, so the virus would have to fundamentally change many different and important genes to evade siRNA detection, and also because in therapeutic settings, many different siRNAs targeting different sites would be used simultaneously. even in viruses that have evolved to have RNAi suppressing proteins, some research shows that synthetic siRNAs can still have an effect.
1-2. i kinda love the slight starchiness and once it starts getting a bit yellow, its perfectly firm and the banana flavor really shines through. even the green ones i'll eat from time to time.
one of the greatest bands of all time. if anyone likes this song, please listen to the rest of this album (13 songs) and their other album repeater as well!
the famously non-religious mandate of heaven
mcdonald's is franchised, so locations are technically owned and operated by independent owners. the franchisee that owned all the israeli locations gave the free meals to the IOF and in response corporate is buying back their locations from the franchisee. corporate shows no intention of stopping doing business in israel.
parachute cargo pants look really cute! and yeah madewell is expensive but they do have good looking stuff, so its worth it i guess? thanks for the recommendation
i'm pretty short (5'4), so finding pants/jeans is always a pain in the ass. but i've had success with old navy and their sizing which has short leg sizes that i dont need to cut or cuff. but thanks for the jewelry recommendation! i'll be looking.
Biden supports a two state solution, Trump supports a one state solution. If you want peace between Palestine and Israel you would vote Biden. If you want war, feel free not to.
"biden is doing genocide, but have you considered trump will do genocide too? so naturally, to stop genocide, we must vote for biden"
thanks for finding the paper and summarizing it! yeah i can definitely see how this wouldn’t really be as effective as they touted, especially with the vector problem. though there are a lot of different viruses that could be used as vectors right? i knew someone who did research into parvoviruses and it seems like they could work too. i still think it’s a cool idea though and i’m hoping it finds more applications.