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Without drugs your body moderates moods and emotions naturally based more or less on what is beneficial or harmful (good things might be connecting with friends, succeeding at a challenge, good food, a comfortable or beautiful environment). Thinking positively is incredibly helpful too.
With drugs though, your feeling of good and happiness is skewed out of balance so only drugs will give you that feeling.
Drugs artificially elevate mood by flooding the brain with neurotransmitters such as dopamine, distorting your sense of well-being and preventing your body from producing these feelings naturally.
It might not be easy but your body will return to normal rythms and emotions with time and healthy habits.