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Im totally sure these are just myths. Its like the americans traveling abroad asking for coke in the bottle. If your traveling and getting something from an inn you know the alcohol is likely safer than whatever standards they have for water. I mean they did not have germ theory but over time people would realize alcohol is safer. If your poor you will eat some marginal things and hide the flavor although granted spices were expensive till they were not and its pretty well known wealthy people put a bunch on to show off and when it got cheap that is when the fancy cooking with proper pairings became a big thing. poor people getting spices im sure at some point was like. omg! you had to be a lord to have a meal like this when I was a kid.
I mean, that would just lead to germ theory (which was kicking around as a minority theory before the microscope). In reality, people will ascribe their problems to all kinds of crazy things, spirits and demons being the most popular. If something is actually poisonous and kills or maims 100% of the time, they'd catch on, but health correlations that are a crapshoot went unnoticed for centuries, because a lot of people were just violently ill from a lot of things.