this post was submitted on 27 Nov 2025
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I’m interested in that feeling of relief some of us get after taking our estradiol dose. I experience it as intense relief that washes over me and bathes me in joy. My color perception dramatically improves at the same time, it’s a very sudden shift.

I seem to only experience it when my blood levels are too low and the new dose enters the blood. With Divigel it’s after 30 minutes have passed, in my case, but only if me levels are low.

Some questions I have:

  • If I don’t feel the relief, am I overdosed?
  • If I do feel the relief, am I underdosed?
  • Why do I and some feel the relief, while others have never felt it?

I don’t expect anyone to know the definitive answers, but maybe you can share your experience? I’m really interested in learning what this is all about.

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[–] Robyn@lemmy.blahaj.zone 6 points 20 hours ago

When it comes to mood, I honestly can’t tell what is because of HRT and what is because of changes in my life, it’s been far too dramatic lately :P

Anyways, I do always look forward to injection day! And I love doing em and feel amazing afterwards! Tho it’s only a mood thing. And again, could just be the joy of continuing a ritual that brings me the desired changes in life. Either way I’m not complaining, either effect is 100% desirable in my opinion! ^^

It’s interesting to me to compare my excitement around injections with my roommate, who sees it more like a chore I have to help remind her to do.