this post was submitted on 27 Nov 2025
27 points (100.0% liked)

Transfem

4866 readers
174 users here now

A community for transfeminine people and experiences.

This is a supportive community for all transfeminine or questioning people. Anyone is welcome to participate in this community but disrupting the safety of this space for trans feminine people is unacceptable and will result in moderator action.

Debate surrounding transgender rights or acceptance will result in an immediate ban.

This community is supportive of DIY HRT. Unsolicited medical advice or caution being given to people on DIY will result in moderator action.

Posters may express that they are looking for responses and support from groups with certain experiences (eg. trans people, trans people with supportive parents, trans parents.). Please respect those requests and be mindful that your experience may differ from others here.

Some helpful links:

Support Hotlines:

founded 2 years ago
MODERATORS
LadyAutumn@lemmy.blahaj.zone
ada@lemmy.blahaj.zone
ada@piefed.blahaj.zone
27
Do you feel relief when taking estrogen? (lemmy.blahaj.zone)
submitted 19 hours ago by Gwen@lemmy.blahaj.zone to c/mtf@lemmy.blahaj.zone
13 comments fedilink hide all child comments
 

I’m interested in that feeling of relief some of us get after taking our estradiol dose. I experience it as intense relief that washes over me and bathes me in joy. My color perception dramatically improves at the same time, it’s a very sudden shift.

I seem to only experience it when my blood levels are too low and the new dose enters the blood. With Divigel it’s after 30 minutes have passed, in my case, but only if me levels are low.

Some questions I have:

  • If I don’t feel the relief, am I overdosed?
  • If I do feel the relief, am I underdosed?
  • Why do I and some feel the relief, while others have never felt it?

I don’t expect anyone to know the definitive answers, but maybe you can share your experience? I’m really interested in learning what this is all about.

you are viewing a single comment's thread
view the rest of the comments
[–] WillStealYourUsername@piefed.blahaj.zone 7 points 18 hours ago* (last edited 18 hours ago)

That's likely your menstruation cycle! Trans women have observed and experienced menstruation since HRT became a thing

We have all the parts needed to experience menstruation, just less of some of the tissues involved, so typically we experience weaker or even not noticeable periods. Some trans women do have very strong periods including period shits, cramps, and large mood swings. It's also possible that how we take HRT affects how noticeable the period is. I'ts not well studied for obvious reasons.

Also, all the different ways of taking HRT have different half lives which is why you feel better or worse when low. Often doctors prescribe people valerate for injections but put people on on a 7 day injection cycle when the half life is 4.5 days, and don't give people a high enough dose for them to have comfortable levels on day 6 and 7. Ideally valerate is instead taken every 5 days to avoid a very large dose and to avoid the 2 days of being too low.

With gel and pills the half life is very short and so you can notice the same day if you are a few hours late, but blockers will change the experience a lot ofc.