this post was submitted on 07 Mar 2025
255 points (96.4% liked)

Science Memes

15822 readers
1960 users here now

Welcome to c/science_memes @ Mander.xyz!

A place for majestic STEMLORD peacocking, as well as memes about the realities of working in a lab.



Rules

  1. Don't throw mud. Behave like an intellectual and remember the human.
  2. Keep it rooted (on topic).
  3. No spam.
  4. Infographics welcome, get schooled.

This is a science community. We use the Dawkins definition of meme.



Research Committee

Other Mander Communities

Science and Research

Biology and Life Sciences

Physical Sciences

Humanities and Social Sciences

Practical and Applied Sciences

Memes

Miscellaneous

founded 2 years ago
MODERATORS
 

Man found missing 90% of his brain defies scientific understanding - most of his skull is filled with water:

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(07)61127-1/fulltext

all 50 comments
sorted by: hot top controversial new old
[–] Neuromancer49@midwest.social 157 points 4 months ago (9 children)

I ran a lot of MRIs for my PhD. I saw somewhere around 100-200 different brains. About 10% of them had abnormalities. Of all the technicians, scientists, and (non-clinical) doctors I spoke with, we all agreed this was a very high rate of discovery. All my friends graduated without seeing anything weird. My advisor liked to joke that I was cursed. Eventually I stopped inviting my friends to do my experiments because I didn't want to deal with the risk of them having an abnormality - thanks to some combination of HIPAA and medical liability laws, I wasn't allowed to say anything about it, even if asked point blank. I didn't like that very much.

I made one exception, as a friend of mine came in for a study and I saw a golf ball sized cyst in his sinus. He had it surgically removed and he told me he stopped snoring the next day. It felt good to make a difference for him.

But, I saw one brain similar to the one documented here. It belongs to one of my close friends. It was harrowing. Entire left hemisphere was malformed, the ventricles were way too big and the cortex was way too thin. But the right side of his brain was underdeveloped, maybe the size of a tennis ball.

The weirdest part, he is 100% normal. In fact, he competed at a high level of college athletics. Normal Cognition, normal motor function, great sense of humor, and a very caring person. Now he has a great job, wife and kid, and we hang out often. But I can't bring myself to say anything, and every time I see his son I wonder about his brain.

[–] SacralPlexus@lemmy.world 21 points 4 months ago

I’m a Neuroradiologist and occasionally people ask me “Have you ever scanned your own brain?” when they find out my profession.

Abso-fucking-lutely not. I’ve seen how many people have random abnormalities that are unknown until discovered incidentally when having an unrelated problem evaluated. Finding something abnormal in my brain would no doubt keep me up at night even if it was something medically considered unimportant. No way I’m going to scan myself just for fun.

[–] Lemming6969@lemmy.world 8 points 4 months ago (1 children)

He's not 100% normal, you just haven't experienced the things he cannot process properly or at all, which is likely a lot of higher reasoning... They just don't affect his day to day, which gives us clues that day to day functioning is very low level and likely mostly autonomous.

[–] Neuromancer49@midwest.social 22 points 4 months ago

Eh, college is hard and so was his sport. Sure, it's not an exhaustive battery of testing but I'm confident to say he's a normal dude.

[–] TeamAssimilation 7 points 4 months ago (1 children)

Imagine what would happen if we substituted the water for more brain.

[–] Neuromancer49@midwest.social 7 points 4 months ago (1 children)

Well it's not quite water, it's cerebrospinal fluid and it plays a lot of important roles in waste clearance, immune protection, protection from concussion, and more.

[–] Agent641@lemmy.world 2 points 4 months ago

It's also a refreshing beverage

[–] Ajen@sh.itjust.works 6 points 4 months ago (1 children)

I'm curious, what exactly are you worried about with your friend? Are the abnormalities you saw linked to a treatable disease?

[–] Neuromancer49@midwest.social 15 points 4 months ago (3 children)

Nope, not related to any disease I've ever seen. The best guess i have is fetal alcohol syndrome but it isn't a perfect match. It's just weird knowing he has a very odd shaped brain. And there's a lot of unknowns surrounding it.

What if he sees another doctor and they mention it to him? Would he be upset I didn't say anything? What if it is linked to some disease and I didn't tell him, and he gets sick?

What if it's hereditary and his kid has it, does it explain the motor delays? The premature birth? The problems they have with him sleeping?

Just a lot of unknowns.

[–] Ajen@sh.itjust.works 9 points 4 months ago

Personally, if I had something like that, that wasn't causing me problems and wasn't linked to future problems, I wouldn't want to know. Especially because of how unknown it is. It sounds like there's no way that information could be of use to anyone other than a researcher, so it actually seems right that you can't share it.

On the other hand, I'm glad your other friend got their sinus checked out.

[–] NoSpotOfGround@lemmy.world 8 points 4 months ago (1 children)

Could you tell him just "you should have another MRI at a clinic"?

That rule does not seem very ethical to me, in any case.

[–] Neuromancer49@midwest.social 6 points 4 months ago (1 children)

In the US getting an MRI for "no reason" can be very expensive. Probably wouldn't have been covered by insurance.

[–] meowMix2525@lemm.ee 2 points 4 months ago

Could you release the already captured images for him to take to a doctor for medical advice?

[–] Lemming6969@lemmy.world 3 points 4 months ago (2 children)

You can tell him he should get a second mri that isn't bound by your rules.

[–] Neuromancer49@midwest.social 4 points 4 months ago (1 children)
[–] Lemming6969@lemmy.world 3 points 4 months ago

Sure but then it's their call and resolves the if they find out issue.

[–] moody@lemmings.world 1 points 4 months ago

It's not like you can just show up to the hospital and demand an MRI

[–] CaptainBlagbird@lemmy.dbzer0.com 6 points 4 months ago

Love your username, especially with that context 😁

[–] Jordan117@lemmy.world 6 points 4 months ago

I think I read that brains like these are basically normal in terms of structure and number of neurons, just compressed by the extra fluid pressure.

[–] beSyl@slrpnk.net 5 points 4 months ago (2 children)

Oh wow, that is so interesting.

Intelligence wise, are the people who have these sort of brains "normal"? Less inteligent? More inteligent?

[–] Neuromancer49@midwest.social 6 points 4 months ago (1 children)

Interesting question. It depends. I linked Ev Fedorenko's Interesting Brain Project at MIT up above, they're doing a deep dive into questions like those.

Broadly speaking, if you're born with these anatomical anomalies, you'll be more or less normal. The article mentions the person in question had an IQ of 70, so that's lower than normal, but not intellectually impaired.

But acquired Brain damage almost always leads to impediments. Strokes and repeated concussions, physical injury, etc.

The brain is "plastic" when you're young, we like to say. That is, it's pliable and can mold into whatever shape it needs to in order to adapt to your environment. That plasticity disappears once you get older. It's how kids can learn language effortlessly - when you're born, you have the most neurons and synapses you'll ever have in your life. You'll keep the same neurons (unless you have a degenerative disorder or kill them with drugs), make new synapses as you learn, but broadly speaking as you grow up you prune synapses that aren't helpful.

This is also why kids can undergo massive resection surgeries (or in the olden days, severing of the corpus callosum) and grow up more or less normal.

[–] toynbee@lemmy.world 3 points 4 months ago

The brain is "plastic" when you're young, we like to say. That is, it's pliable and can mold into whatever shape it needs to in order to adapt to your environment. That plasticity disappears once you get older

So it's good that we're getting microplastics in our brains because it allows easier development as we age!

[–] funkless_eck@sh.itjust.works 2 points 4 months ago

intelligence is a very hard thing to quantify. People who are good at math might be terrible at writing plays, both of which are intelligent processes.

[–] toynbee@lemmy.world 1 points 4 months ago (1 children)

My advisor liked to joke that I was cursed.

It didn't have quite the same level of personal impact, but I used to associate with a geologist who said something similar about me and geodes.

[–] captainlezbian@lemmy.world 4 points 4 months ago (1 children)

Kept finding geodes filled with fresh human blood huh?

load more comments (1 replies)
[–] meme_historian@lemmy.dbzer0.com 29 points 4 months ago (1 children)

Also, you'd think the title was edited for meme-ing purposes...but no. This is just dead ass what they printed in The Lancet 😂

[–] Kusimulkku@lemm.ee 4 points 4 months ago

Every time this is mentioned I get the biggest chuckle out of him being a French civil servant.

Explains why it went unnoticed.

[–] Elaine@lemm.ee 26 points 4 months ago (1 children)

When I got an MRI I learned I have some empty spaces in my brain that normally close during infancy. I was there because my family has a genetic marker for cavernous venous malformations primarily in the brain. Luckily it doesn’t affect our intelligence, we just “die of headaches”.

[–] bizzle@lemmy.world 17 points 4 months ago

Average middle manager

Holy shit. That’s fucking wild. I know the brain is adaptable, particularly to things that occur during childhood, but… damn.

[–] meme_historian@lemmy.dbzer0.com 10 points 4 months ago

I have SO many questions

[–] yesman@lemmy.world 9 points 4 months ago (1 children)

If we could just let go of the Yakubian myth that more brains = smarter, this wouldn't be so surprising.

[–] Frenchy@aussie.zone 3 points 4 months ago (1 children)

I mean the guy has an IQ of 70 so it’s not like he’s of normal intelligence either.

[–] yesman@lemmy.world 4 points 4 months ago

Measuring the volume of a skull was once a valid way to determine intellect. We make fun of people who believed that, but IQ is arguably a worse instrument, and certainly no better.

The problem is you can't measure intelligence any more than you can measure charm or beauty. All instruments who claim to do so are doomed to embarrass the people who use them.

[–] bjoern_tantau@swg-empire.de 7 points 4 months ago (2 children)

Ew, I don't want to see other people's brains on here!

[–] latenightnoir@lemmy.world 4 points 4 months ago

Yaaay, new nightmare unlocked!

[–] JackFrostNCola@lemmy.world 4 points 4 months ago (1 children)

Weird, you can just make out letters in one angle, i see a M and G... Was the subject wearing a hat during the scan?

[–] smeg@feddit.uk 2 points 4 months ago

I see an LV